Keap1/Nrf2/ARE activator 2, CAS [[3105470-83-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-180155
Supplier Catalog Number:
HY-180155
Alternative Catalog Number:
MCE-HY-180155-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Keap1/Nrf2/ARE activator 2 is an activator of Keap1/Nrf2/ARE pathway and non-competitively inhibits AChE with an IC50 of 14.79 µM and a Ki of 1.35 µM. Keap1/Nrf2/ARE activator 2 promotes Nrf2 nuclear translocation, leading to antioxidant gene upregulation and enhanced cellular defense against oxidative stress. Keap1/Nrf2/ARE activator exhibits robust neuroprotection against both H2O2- and Scopolamine (SCA) (HY-N0296)-induced injury in PC12 cells. Keap1/Nrf2/ARE activator 2 ameliorates memory impairment and the neuro-inflammation associated with SCA-initiated cognitive dysfunction in a zebrafish model. Keap1/Nrf2/ARE activator 2 can be used for the research of Alzheimers disease[1].
Molecular Weight:
333.13
CAS Number:
[3105470-83-2]
Formula:
C15H9BrO4
Target:
Cholinesterase (ChE),Heme Oxygenase (HO),Interleukin Related,Keap1-Nrf2,Quinone Reductase,Reactive Oxygen Species (ROS),TNF Receptor
Application Notes:
MCE Product type: Reference compound
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