B-Raf IN 20 (Compound Z-001) is a novel B-RAF inhibitor with an IC50 value of 37.80 nM. B-Raf IN 20 binds to DFG-out/C-helix-in conformation in the B-RAF kinase. B-Raf IN 20 has anti-cancer activity against non-small cell lung cancer[1].
Molecular Weight:
622.68
Formula:
C34H37F3N4O4
Target:
Raf
Application Notes:
MCE Product type: Reference compound
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