RN486 is a potent, selective and orally active Btk inhibitor with an IC50 of 4.0 nM and a Kd of 0.31 nM. RN486 is less active for other kinases. RN486 can be used for rheumatoid arthritis and systemic lupus erythematosus research[1][2][3].
Molecular Weight:
606.69
Purity:
99.54
CAS Number:
[1242156-23-5]
Formula:
C35H35FN6O3
Target:
Btk
Application Notes:
MCE Product type: Reference compound
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