cGAS-IN-8 is an indazole cyclic GMP-AMP synthase (cGAS) inhibitor with an IC50 of 6 nM for human cGAS. cGAS-IN-8 inhibits cGAMP production in THP-1 cells with an IC50 of 0.12 µM. cGAS-IN-8 does not inhibits hERG activity. cGAS-IN-8 can be used for the research of autoimmune diseases[1].
Molecular Weight:
479.81
Formula:
C18H18ClF4N5O4
Target:
Cyclic GMP-AMP Synthase
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
