Anticancer agent 289 is a H2O2-responsive anticancer prodrug. Anticancer agent 289 exhibits H2O2-inducible DNA-alkylating activity, selectively inhibits the proliferation of high ROS-expressing cancer cells over nonmalignant cells, markedly suppresses tumor growth without observable toxicity in vivo. Anticancer agent 289 can be used for triple-negative breast cancer (TNBC) research[1].
Molecular Weight:
289.99
Formula:
C12H18BCl2NO2
Target:
Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound1
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