TGR5 agonist 8 (Compound 7i) is a TGR5 agonist with an EC50 of 571 nM. TGR5 agonist 8 significantly reduced blood glucose and food intake in acute diabetic mice and long-term inhibited the mices appetite. TGR5 agonist 8 can be used for research on diabetes and obesity[1].
Molecular Weight:
603.72
Formula:
C37H33N9
Target:
G protein-coupled Bile Acid Receptor 1
Application Notes:
MCE Product type: Reference compound1
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