PARP1 degrader 1 (Compound 2c) is a comparatively potent PARP1 HyT degrader (DC50: 618 nM for intracellular PARP-1). PARP1 degrader 1 is also a HyT-Olaparib (HY-10162) conjugate. PARP1 degrader 1 induces UPR/autophagy, thus facilitating the degradation of PARP-1. PARP1 Degrader 1 can be used in the research of cancer[1].
Molecular Weight:
699.81
Formula:
C42H42FN5O4
Target:
Autophagy,Drug Derivative,PARP
Application Notes:
MCE Product type: Reference compound
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