P-gp-IN-33 (Compound 17a) is a P-gp inhibitor. P-gp-IN-33 binds the Verapamil (HY-14275)-binding pocket of P-gp. P-gp-IN-33 shows higher cytotoxicity against resistant non-small cell lung carcinoma cells than against non-resistant non-small cell lung carcinoma cells[1].
Molecular Weight:
738.83
Formula:
C40H46N6O8
Target:
P-glycoprotein
Application Notes:
MCE Product type: Reference compound
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