S-312 is a calcium antagonist with a bicyclic dihydrothienopyridine structure. S-312 can relax the helical strips of various isolated rabbit arteries procontracted with high potassium depolarizaiton. S-312 competitively imhibits calcium-induced contractions in depolarized basilar and femoral arteries. S-312 increases AV nodal conduction time in Langenedorff-perfused isolated rabbit hearts. S-312 exhibits vasculoselectivity, particularly for cerebral vessel[1].
Molecular Weight:
386.46
CAS Number:
[120004-07-1]
Formula:
C20H22N2O4S
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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