E 6080 is an orally active and selective 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 0.2 µM in rat basophilic leukemia cell. E 6080 shows potent inhibitory effects on the release of leukotrienes. E 6080 inhibits the bronchospasm induced by antigen (ovalbumin) inhalation in sensitized conscious guinea pigs. E 6080 can be used for the study of asthma[1][2][3].
Molecular Weight:
413.94
CAS Number:
[120164-49-0]
Formula:
C17H20ClN3O3S2
Target:
Leukotriene Receptor,Lipoxygenase
Application Notes:
MCE Product type: Reference compound
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