Nitromemantine, CAS [[765890-91-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-180370
Supplier Catalog Number:
HY-180370
Alternative Catalog Number:
MCE-HY-180370-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Nitromemantine is a nitrate derivative of Memantine (HY-B0591) and is a dual-functional NMDAR antagonist. Nitromemantine exhibits significant efficacy in rodent models of cerebral infarction through a dual mechanism of blocking channels and regulating receptors via NO/redox regulation. Nitromemantine can target ischemic neurons under hypoxic conditions and enhance its activity. Nitromemantine inhibits the current induced by NMDA, with its IC50 being 2.4 µM. Nitromemantine can be used for the study of cerebral ischemic stroke[1].
Molecular Weight:
268.35
CAS Number:
[765890-91-3]
Formula:
C14H24N2O3
Target:
Drug Derivative,iGluR
Application Notes:
MCE Product type: Reference compound1
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