CAI0019 is an orally active alpha-carbonic anhydrase inhibitor based on the Acetazolamide (HY-B0782) framework. CAI0019 exhibits narrow-spectrum antibiofilm activity, with its MIC50 being 0.094 µM and MIC90 being 0.39 µM. CAI0019 selectively inhibits Enterococcus in a septic peritonitis mouse model, without affecting most intestinal commensal bacteria[1].
Molecular Weight:
318.42
CAS Number:
[2446169-48-6]
Formula:
C11H18N4O3S2
Target:
Bacterial,Carbonic Anhydrase,Drug Derivative
Application Notes:
MCE Product type: Reference compound
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