TrmD-IN-1 (compound 8h) is a selective Staphylococcus aureus tRNA m1 G37 methyltransferase (TrmD) inhibitor with a KD of 2.48 µM and an IC50 of 1.16 µM. TrmD-IN-1 exhibits selectivity over E. coli (KD > 30 µM) and H. influenzae TrmD (KD > 30 µM) and Trm5 (IC50 > 30 µM)[1].
Molecular Weight:
287.28
Formula:
C11H13N9O
Target:
RNA MTase
Application Notes:
MCE Product type: Reference compound
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