CDK2-IN-53 (compound 9) is a CDK2 inhibitor with anticancer activity. CDK2-IN-53 selectively inhibits the proliferation of HCT-116 and MCF-7cells with IC50 values of 13.89 and 7.65 µM, respectively, while showing lower cytotoxicity toward normal lung fibroblast (WI-38) cells (IC50 = 71.24 µM). CDK2-IN-53 can be used for cancer research, such as colon and breast cancer[1].
Molecular Weight:
531.03
Formula:
C27H23ClN6O2S
Target:
CDK
Application Notes:
MCE Product type: Reference compound
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