UCB1244283 is a synaptic vesicle glycoprotein 2A (SV2A) allosteric modulator. UCB1244283 binds to a secondary ligand-binding site in SV2A and enhances orthosteric ligand engagement when the orthosteric site is occupied, by stabilizing the occluded state and slowing ligand dissociation. UCB1244283 shows a clear protective effect against both tonic and clonic convulsions in sound-sensitive mice. UCB1244283 can be used for epilepsy research[1][2][3].
Molecular Weight:
311.42
CAS Number:
[300587-89-7]
Formula:
C20H25NO2
Target:
Synaptic Vesicle Proteins
Application Notes:
MCE Product type: Reference compound
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