TCR-IN-2 (Compound A-68) is a TCR inhibitor. TCR-IN-2 inhibits the release of IFNgamma and IL-2. TCR-IN-2 inhibits the time-dependent phosphorylation of CD3zeta. TCR-IN-2 inhibits TCR-mediated T cell activation, both in response to anti-CD3 antibodies and in response to human cells with unmatched HLA[1].
Molecular Weight:
447.45
CAS Number:
[2375043-73-3]
Formula:
C24H24F3NO4
Target:
CD3,IFNAR,Interleukin Related,MHC
Application Notes:
MCE Product type: Reference compound
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