G6374 is an IRE1 PROTAC degrader with a DC50 of 0.04 µM. G6374 induces efficient ubiquitination and degradation of IRE1. G6374 selectively inhibits IRE1-dependent cancer-cell proliferation[1].
Molecular Weight:
883.16
Formula:
C47H66N10O5S
Target:
IRE1
Application Notes:
MCE Product type: Reference compound
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