PKM2 activator 11 (Compound 23) is a PKM2 activator with an AC50 value of 92.12 nM. PKM2 activator 11 promotes PKM2 tetramerization and inhibits its nuclear translocation. PKM2 activator 11 suppresses glycolysis and the PKM2/STAT3 signaling pathway. PKM2 activator 11 induces Apoptosis. PKM2 activator 11 exhibits anti-CRC activity in vitro with potency and selectivity[1].
Molecular Weight:
457.54
Formula:
C27H23NO4S
Target:
Apoptosis,Pyruvate Kinase,STAT
Application Notes:
MCE Product type: Reference compound
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