RIPK1-IN-39, CAS [[3065634-42-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-180806
Supplier Catalog Number:
HY-180806
Alternative Catalog Number:
MCE-HY-180806-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
RIPK1-IN-39 (compound 2) is a potent and selective RIPK1 inhibitor (IC50 = 69.40 nM) exhibiting >100-fold selectivity over RIPK3 (IC50 = 6946 nM). RIPK1-IN-39 protects HT-22 and HT-29 cells from necroptosis by inhibiting the phosphorylation and activation of the RIPK1-RIPK3-MLKL pathway. RIPK1-IN-39 demonstrates neuroprotective effects in a rat model of middle cerebral artery occlusion (MCAO). RIPK1-IN-39 can be used for acute ischemic stroke (AIS) research[1].
Molecular Weight:
525.60
CAS Number:
[3065634-42-3]
Formula:
C29H24FN5O2S
Target:
Apoptosis,RIP kinase
Application Notes:
MCE Product type: Reference compound
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