YCH3292, a derivative of YCH189 (HY-155993) is a potent, selective and orally active PARP1/2 inhibitor with IC50 both gammaH2AX, P-RPA32, and P-Chk1 and induce tumor cells S or G2/M phase arrest and apoptosis. YCH3292 can inhibit tumor growth in MC38 xenograft model[1].
Molecular Weight:
510.52
CAS Number:
[3049753-10-5]
Formula:
C28H23FN6O3
Target:
PARP
Application Notes:
MCE Product type: Reference compound
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