TGR5 agonist 9, CAS [[2931879-67-1]] Preis auf Anfrage

Product Overview

• Article Name: TGR5 agonist 9, CAS [[2931879-67-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-180845
• Supplier Catalog Number: HY-180845
• Alternative Catalog Number: MCE-HY-180845-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

TGR5 agonist 9 is a highly selective and orally active TGR5 allosteric agonist with EC50 values for hTGR5 and mTGR5 of 0.48 and 0.49 µM, respectively. TGR5 agonist 9 can recruit beta-arrestin 1 (EC50 = 78.8 µM) and beta-arrestin 2 (EC50 = 12.3 µM), and has a higher efficacy in cAMP accumulation (EC50 = 0.48 µM). TGR5 agonist 9 exhibits a significant hypoglycemic effect in the ICR mouse model. TGR5 agonist 9 can be used for research on diabetes[1].

Product Properties

• Molecular Weight: 475.70
• CAS Number: [2931879-67-1]
• Formula: C29H49NO4
• Target: G protein-coupled Bile Acid Receptor 1

Application Notes

• Application Notes: MCE Product type: Reference compound