8012-3246 is a selective PLK2 inhibitor with an IC50 of 774.5 nM. 8012-3246 suppresses GSK3beta phosphorylation. 8012-3246 exhibits potent anticancer activity against colorectal cancer[1].
Molecular Weight:
347.33
CAS Number:
[421586-94-9]
Formula:
C18H13N5O3
Target:
GSK-3,Polo-like Kinase (PLK)
Application Notes:
MCE Product type: Reference compound
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