RSK4-IN-2 (compound 16o) is a potent, orally active RSK4 inhibitor with an IC50 of 17 nM. RSK4-IN-2 suppresses esophageal squamous cell carcinoma (ESCC) cell growth and invasion, by inhibiting phosphorylation of RSK4 downstream targets. RSK4-IN-2 inhibits tumor growth and metastasis in ESCC mouse models. RSK4-IN-2 can be used for ESCC research[1].
Molecular Weight:
348.36
CAS Number:
[3034203-03-4]
Formula:
C17H16N8O
Target:
Ribosomal S6 Kinase (RSK)
Application Notes:
MCE Product type: Reference compound
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