FQI2-34 is an orally active TFCP2 (LSF) small molecule allosteric inhibitor. FQI2-34 directly binds to the LSF protein (Ki = 63 nM), inhibits the oligomerization of LSF, efficiently suppresses the transcriptional activity of LSF (IC50 = 48 nM), and interferes with the SF-DNA interaction. FQI2-34 exhibits significant anti-proliferative activity against Huh7 cells and induces tumor regression in mouse models. FQI2-34 can be used for research on liver cancer[1].
Molecular Weight:
352.38
CAS Number:
[2762499-38-5]
Formula:
C20H20N2O4
Target:
Connective Peptide
Application Notes:
MCE Product type: Reference compound
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