FBPase-IN-6 (Compound 96) is an orally active FBPase inhibitor with an IC50 value of 1.769 µM. FBPase-IN-6 modulates AMPK/mTORC1/S6K signaling pathways. FBPase-IN-6 improves glucose tolerance, enhances insulin sensitivity, and promotes insulin secretion in type 2 diabetic mice[1].
Molecular Weight:
513.99
Formula:
C25H24ClN3O5S
Target:
AMPK,FBPase,mTOR,Ribosomal S6 Kinase (RSK)
Application Notes:
MCE Product type: Reference compound
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