Phe-PEG1-Dasa, CAS [[3037776-73-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-180962
Supplier Catalog Number:
HY-180962
Alternative Catalog Number:
MCE-HY-180962-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Phe-PEG1-Dasa is a BCR-ABL PROTAC degrader, with its DC50 being 1.56 nM. Phe-PEG1-Dasa uses a single amino acid (Phe) as the E3 ligand and employs the N-end rule pathway to induce the degradation of the target protein, significantly reducing the molecular size, thus being called a mini-PROTAC. Phe-PEG1-Dasa significantly inhibits the proliferation of K562 cells. Phe-PEG1-Dasa can be used for the study of leukemia[1].
Molecular Weight:
750.31
CAS Number:
[3037776-73-8]
Formula:
C36H44ClN9O5S
Target:
Bcr-Abl,PROTACs
Application Notes:
MCE Product type: Reference compound
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