GMB-805 is a BCR-Abl PROTAC degrader with a DC50 of 30 nM in K562 cells. GMB-805 exerts antiproliferative activity in K562 cells. GMB-805 exhibits potent anti-tumor activity with favorable safety profile in vivo. GMB-805 can be used for chronic myeloid leukemia research[1][2].
Molecular Weight:
894.39
CAS Number:
[2489876-41-5]
Formula:
C42H46ClF2N9O7S
Target:
Bcr-Abl,PROTACs
Application Notes:
MCE Product type: Reference compound
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