PROTAC PLK1 Degrader-2 (Compound NC1) is a PLK1 PROTAC degrader with an Kd of 6.06 µM. PROTAC PLK1 Degrader-2 significantly inhibits the proliferation of HeLa cells, induces cell cycle arrest and apoptosis. PROTAC PLK1 Degrader-2 exhibits significant anti-tumor activity in a HeLa cell xenograft tumor mouse model. PROTAC PLK1 Degrader-2 can be used for the study of cervical cancer.
Molecular Weight:
2808.30
Formula:
C116H216N57O23P
Target:
Apoptosis,Polo-like Kinase (PLK),PROTACs
Application Notes:
MCE Product type: Reference compound
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