Abeta aggregation-IN-5 is a brain-penetrant amyloid-beta aggregation inhibitor. Abeta aggregation-IN-5 inhibits Abeta aggregation/oligomerization, rescues cells from AB/ROS toxicity and reduces microglial activation/NO production. Abeta aggregation-IN-5 reduces amyloid burden, neuroinflammation, microglial activation in APP/PSEN1 mice. Abeta aggregation-IN-5 can be used for the research of Alzheimers disease[1].
Molecular Weight:
563.64
Formula:
C32H37NO8
Target:
Amyloid-beta
Application Notes:
MCE Product type: Reference compound
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