PRE-084 is a highly selective sigma1 receptor (S1R) agonist, with an IC50 of 44 nM. PRE-084 exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway[1][2][3][4].
Molecular Weight:
317.42
CAS Number:
[138847-85-5]
Formula:
C19H27NO3
Target:
Akt,NO Synthase,Sigma Receptor
Application Notes:
MCE Product type: Reference compound
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