PRE-084 hydrochloride is a highly selective sigma1 receptor (S1R) agonist, with an IC50 of 44 nM. PRE-084 hydrochloride exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 hydrochloride also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway[1][2][3][4].
Molecular Weight:
353.88
Purity:
99.92
CAS Number:
[75136-54-8]
Formula:
C19H28ClNO3
Target:
Akt,NO Synthase,Sigma Receptor
Application Notes:
MCE Product type: Reference compound
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