Multitarget AD-IN-5 (Compound 20), 9-Aminoacridine (HY-B1422) derivative, is a neuroprotective agent. Multitarget AD-IN-5 shows IC50 values of 0.614, 0.448, 3.73 and 1.55 µM for hAChE, hBChE, hMAO-A and hMAO-B. Multitarget AD-IN-5 can reduce length and diameter of Abeta42 fibers, and decrease the number of fibers per unit area. Multitarget AD-IN-5 shows a CC50 of 95 µM for SH-SY5Ycells. Multitarget AD-IN-5 can be used for research of Alzheimers disease[1].