EGFR/COX-2-IN-3 is a selective EGFR/COX-2 dual inhibitor with IC50 values of 0.098 µM and 0.05 µM, respectively. EGFR/COX-2-IN-3 is predicted to have oral activity and blood-brain barrier permeability. EGFR/COX-2-IN-3 exhibits both potent analgesic activity and anti-glioblastoma effects. EGFR/COX-2-IN-3 can be used in the research of tumors such as glioblastoma[1].
Molecular Weight:
375.47
Formula:
C22H25N5O
Target:
COX,EGFR
Application Notes:
MCE Product type: Reference compound
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