STING-IN-18 is an orally active STING inhibitor. STING-IN-18 exhibits an IC50 of 86 nM against STING in murine RAW-LuciaTM ISG cells. STING-IN-18 inhibits STING activation and blocks downstream signaling pathways. STING-IN-18 suppresses kidney injury and inflammation. STING-IN-18 can be used for the research of autoimmune and inflammatory diseases[1].
Molecular Weight:
339.37
Formula:
C18H18FN5O
Target:
CXCR,Interleukin Related,Reactive Oxygen Species (ROS),STING
Application Notes:
MCE Product type: Reference compound
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