PROTAC HMGCR Degrader-2, CAS [[2715104-46-2]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC HMGCR Degrader-2, CAS [[2715104-46-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-181134
• Supplier Catalog Number: HY-181134
• Alternative Catalog Number: MCE-HY-181134-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC HMGCR Degrader-2 is a HMGCR PROTAC degrader with an IC50 value of 0.25 µM. PROTAC degrades HMGCR-2 in Insig-silenced HepG2 cells with a DC50 of 0.12 µM. PROTAC HMGCR Degrader-2 takes PROTAC HMGCR Degrader-1 (HY-171823) as the oral prodrug. PROTAC HMGCR Degrader-2 degrades HMGCR by the VHL-dependent ubiquitin-proteasome system and reduces cellular cholesterol in HepG2 cells. PROTAC CDK2/4/6 Degrader-2 can be used for hyperlipidemia research[1].

Product Properties

• Molecular Weight: 978.29
• CAS Number: [2715104-46-2]
• Formula: C53H79N5O10S
• Target: PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound