CK2-TN03, CAS [[313226-24-3]]

Catalog Number: MCE-HY-181442
Article Name: CK2-TN03, CAS [[313226-24-3]]
Biozol Catalog Number: MCE-HY-181442
Supplier Catalog Number: HY-181442
Alternative Catalog Number: MCE-HY-181442-25MG,MCE-HY-181442-50MG,MCE-HY-181442-10MG,MCE-HY-181442-5MG,MCE-HY-181442-10MMX1ML
Manufacturer: MedchemExpress
Category: Biochemikalien
CK2-TN03 is an ATP-competitive casein kinase 2 (CK2) inhibitor, with an IC50 of 165 nM and a Ki of 20 nM. CK2-TN03 inhibits CK2-mediated survivin activation and reduces CK2-dependent phosphorylation levels of BRD4/MYCN and AKT1. CK2-TN03 exerts anti-neuroblastoma effects by inhibiting survivin, leading to mitotic catastrophe and apoptosis of cancer cells. CK2-TN03 can be used in studies related to neuroblastoma[1].
Molecular Weight: 326.37
Purity: 98.02
CAS Number: [313226-24-3]
Formula: C17H14N2O3S
Target: Akt,Apoptosis,Casein Kinase,Caspase,Epigenetic Reader Domain,MDM-2/p53,Survivin
Application Notes: MCE Product type: Reference compound