CVN14 is a potent, selective and brain-penetrant CD38 inhibitor with human IC50 19 nM, mouse IC50 2.4 nM. CVN14 binds uncompetitively to form a complex with CD38 and ADPR, and inhibits CD38 enzymatic activity. CVN14 can be used for the research of neurodegenerative diseases[1].
Molecular Weight:
382.38
CAS Number:
[2925663-26-7]
Formula:
C17H21F3N6O
Target:
CD38
Application Notes:
MCE Product type: Reference compound
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