Nampt-IN-17, CAS [[3077970-78-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-181578
Supplier Catalog Number:
HY-181578
Alternative Catalog Number:
MCE-HY-181578-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Nampt-IN-17 is an selective orally active NAMPT inhibitor with a human NAMPT IC50 of 17 nM and Ki of 25.9 nM. Nampt-IN-17 depletes intracellular NAD+ and ATP, disrupts mitochondrial membrane potential, suppresses cell proliferation, self-renewal, invasion, and migration, induces cell-cycle arrest and apoptosis. Nampt-IN-17 exhibits selective activity against NAPRT-deficient gastric cancer cells. Nampt-IN-17 can be used for the research of NAPRT-deficient gastric cancer[1].
Molecular Weight:
461.53
CAS Number:
[3077970-78-3]
Formula:
C26H28FN5O2
Target:
Apoptosis,NAMPT
Application Notes:
MCE Product type: Reference compound
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