DLK-IN-2 is a selective inhibitor of DLK and neuroprotective agent. DLK-IN-2 shows no significant inhibition against CYPs 3A4, 2D6 and 2C9. DLK-IN-2 inhibits acute axonal palmitoylation of DLK, blocks DLK-dependent pro-degenerative axon-to-soma retrograde signaling and suppresses c-Jun phosphorylation. DLK-IN-2 can be used for the mechanistic study of neurodegenerative diseases[1].
Molecular Weight:
444.97
CAS Number:
[883012-32-6]
Formula:
C23H25ClN2O3S
Target:
MAP3K
Application Notes:
MCE Product type: Reference compound
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