P300-IN-6 is an orally active histone acetyltransferase p300 HAT domain inhibitor with human IC50 values of 7 nM. P300-IN-6 suppresses c-Myc expression, decreases H3K18ac and H3K27ac levels, and inhibits cancer cell proliferation.P300-IN-6 suppresses tumor growth in xenograft mouse models.P300-IN-6 can be used for the research of multiple myeloma[1].
Molecular Weight:
454.52
CAS Number:
[3034595-62-2]
Formula:
C26H26N6O2
Target:
c-Myc,Histone Acetyltransferase
Application Notes:
MCE Product type: Reference compound
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