CXCR2 antagonist 10 (Compound 10b) is a CCR2 antagonist with an IC50 of 0.48 µM. CXCR2 antagonist 10 also exhibits antagonistic activity against CXCR2/CCR7, with IC50 values of 4.18 µM and 2.07 µM, respectively. CXCR2 antagonist 10 is applicable for cancer research[1].
Molecular Weight:
384.38
Formula:
C15H15F3N6OS
Target:
CCR,CXCR
Application Notes:
MCE Product type: Reference compound
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