NK3R antagonist-1 is an orally active, blood-brain barrier permeable neurokinin-3 receptor (NK3R) antagonist with an IC50 of 53.61 nM. NK3R antagonist-1 reduces plasma luteinizing hormone (LH) levels in ovariectomized rat models. NK3R antagonist-1 is applicable to research related to menopausal hot flushes[1].
Molecular Weight:
395.45
Formula:
C20H18FN5OS
Target:
Neurokinin Receptor
Application Notes:
MCE Product type: Reference compound
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