GCB-27a is a CD1d-binding immunostimulant and antitumor agent. GCB-27a binds to CD1d to form a stable complex and presents it to NKT cells, enhancing hydrophobic interactions within the A pocket of CD1d through branched-chain conformation restriction. GCB-27a induces a Th1-biased immune response, drives IFN-gamma production and limits IL-4 levels. GCB-27a is applicable to research related to melanoma lung metastasis[1].
Molecular Weight:
894.31
Formula:
C52H95NO10
Target:
CD1
Application Notes:
MCE Product type: Reference compound
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