DOT1L808 is a potent and highly selective DOT1L PROTAC degrader with a DC50 value of 5 nM. DOT1L808 can promote the ubiquitination and degradation of DOT1L. DOT1L808 exhibits antitumor activity in an orthotopic leukemia model[1].
Molecular Weight:
1301.89
Formula:
C61H72ClF3N14O9S2
Target:
Histone Methyltransferase,PROTACs
Application Notes:
MCE Product type: Reference compound
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