CL121 is a Glutaminyl Cyclase inhibitor with an IC50 of 0.07 µM against human sQC and an IC50 of 0.54 µM against human gQC. CL121 reduces the level of pyroglutamate (pE)-modified CD47 on the surface of cancer cells. CL121 exhibits anti-tumor activity against triple-negative breast cancer[1].
Molecular Weight:
351.40
Formula:
C20H21N3O3
Target:
Amyloid-beta,CD47
Application Notes:
MCE Product type: Reference compound
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