MRS8432 is an ABCG2 modulator with an EC50 of 7.5 nM against human ABCG2. MRS8432 activates ABCG2 ATPase activity. MRS8432 partially inhibits ABCG2-mediated substrate transport. MRS8432 is applicable to research related to cancer multidrug resistance[1].
Molecular Weight:
694.09
Formula:
C35H26ClF2N9O3
Target:
BCRP
Application Notes:
MCE Product type: Reference compound
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