SOS1/KRAS-IN-2 (Compound 20) is a SOS1::KRASG12C protein-protein interaction inhibitor with a IC50 of 4.11 nM. SOS1/KRAS-IN-2 blocks the interaction between SOS1 and KRASG12C. SOS1/KRAS-IN-2 induces cell Apoptosis. SOS1/KRAS-IN-2 exhibits anticancer activity against colorectal cancer and tongue squamous cell carcinoma[1].
Molecular Weight:
441.45
Formula:
C23H22F3N5O
Target:
Apoptosis,Ras,SOS1
Application Notes:
MCE Product type: Reference compound
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