Atz-L5 is a PD-L1 PTAC (PSMA-targeted chimera) degrader (DC50: 18 pM in PC3-PIP cells, 2 pM in LNCaP cells) and LYTAC. Atz-L5 promotes lysosomal degradation of PD-L1 in PSMA-positive prostate cancer cells. Atz-L5 is applicable to the research of prostate cancer[1].
Molecular Weight:
1798.89
Formula:
C82H119N13O32
Target:
LYTACs,PD-1/PD-L1,PSMA
Application Notes:
MCE Product type: Reference compound
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