IKKbeta-IN-6, CAS [[3117527-91-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-181836
Supplier Catalog Number:
HY-181836
Alternative Catalog Number:
MCE-HY-181836-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
IKKbeta-IN-6 is an antitumor agent. IKKbeta-IN-6 inhibits IKKbeta (IC50: 18.24 µM), thereby suppressing the phosphorylation of p65 and IkappaBalpha, blocking the nuclear translocation of p65, and subsequently regulating genes controlled by NF-kappaB. IKKbeta-IN-6 also targets topoisomerase I (Topo I), induces DNA damage, ROS accumulation, loss of mitochondrial membrane potential, and S-phase arrest. IKKbeta-IN-6 is applicable to related research on colorectal cancer[1].
Molecular Weight:
758.77
CAS Number:
[3117527-91-7]
Formula:
C43H38N2O11
Target:
Apoptosis,Bcl-2 Family,IKK,NF-kappaB,Reactive Oxygen Species (ROS),Topoisomerase
Application Notes:
MCE Product type: Reference compound
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