AChE-IN-109 is a potent mixed-type cholinesterase inhibitor with significantly stronger inhibitory activity against AChE than BChE. AChE-IN-109 has IC50 values of 0.55 µM and 12.45 µM against AChE and BChE, respectively. AChE-IN-109 inhibits cholinesterases through a mixed-type mechanism, binds to both the catalytic active site (CAS) and peripheral anionic site (PAS) of AChE. AChE-IN-109 can be used for the study of Alzheimers disease (AD)[1].
Molecular Weight:
497.59
Formula:
C28H31N7O2
Target:
Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound
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